PDF) Clearance Prediction Methodology Needs Fundamental Improvement: Trends Common to Rat and Human Hepatocytes/Microsomes and Implications for Experimental Methodology

Evidence of the need for modified well-stirred model in vitro to

In Vitro - in Vivo Extrapolation of Hepatic Clearance in

Molecules, Free Full-Text

PDF) Clearance Prediction Methodology Needs Fundamental Improvement: Trends Common to Rat and Human Hepatocytes/Microsomes and Implications for Experimental Methodology

Virtual experiments provide plausible explanations for IVIVE

Incorporating Measures of Variability and Uncertainty into the Prediction of in Vivo Hepatic Clearance from in Vitro Data

Mechanistic insights from comparing intrinsic clearance values

PDF) Clearance Prediction Methodology Needs Fundamental

PDF] Clearance Prediction Methodology Needs Fundamental